From the expression patterns of Tff1 in the Gp130FF gastric tumors, we can infer that the conditional deletion of Yap1 with the Tff1-driven Cre-recombinase targeted the parietal cells, chief cells, foveolar cells, tumor epithelial cells, mucous neck cells, tuft cells, and neuroendocrine cells, thereby inducing a potent anti-tumor effect. This evidence concerns the gene YAP1 and gastric neoplasm.