MAPT and neurodegenerative disease: In this study, we have examined the ability of our GFET biosensor, which is able to detect as few as seven Sars-CoV2 viruses [and 100 spike and nucleoproteins per 10 μL sample (18, 31, 32)], for early, simple, at-home, and POC detection of Aβ, Tau, and αS, biomarkers for AD, PD, and neurodegenerative diseases.