The high IL‐10 expression (frequency ≥ 10.7%) haplotype combination GCC/GTA, GCC/ATA, and GCC/GCA was predominantly present (48.7% vs. 26.8%) in severely affected patients with GBS compared to mild form and reached statistical significance (p = 0.026, OR = 0.40, 95% CI = 0.19–0.90, pc = 0.078; Table 4). This evidence concerns the gene IL10 and Guillain-Barre syndrome.