In glioma, miR-181b acts as a tumor suppressor by inhibiting tumor growth and invasion and inducing apoptosis, possibly through targeting the NF-κB and EMT pathways.20 Characterizing the role of miRNAs like miR-181b in HB may lead to the development of more effective and personalized therapies for a wide range of malignancies. This evidence concerns the gene NFKB1 and glioma.