EMT is a process by which epithelial cells acquire mesenchymal properties, allowing them to invade surrounding tissues and migrate to distant organs, and activation of the JAK/STAT signaling pathway can induce cellular EMT and thus promote tumor metastasis.25 In our study, we have shown that the overexpression of miR-181b leads to the downregulation of E-cadherin and upregulation of N-cadherin, snail, and vimentin, which are characteristic markers of EMT. The gene discussed is SOAT1; the disease is neoplasm.