IL4 and asthma: Lan Huangqi et al. used Litsea pungens Hemsl and Lonicerae Japonicae Caulis extracts on asthma model mice and found that its mechanism of action was reducing the levels of IgE, IL-4, IL-5, and IL-10 contained in the serum, increase the level of IFN-γ, and weaken the expression of GATA-3 protein, confirming that Lonicerae Japonicae Caulis can be used to improve airdoritis in the asthmatic mice (Lan et al., 2020a).