Many of these risk factors for CLBP have been analyzed in our patients with MD2 (e.g., age, smoking, BMI, depression, presence of chronic musculoskeletal pain except LBP), but their influence was not confirmed in this cohort, probably due to the fact that this is not the general population but patients with a muscular disease where trunk muscle dysfunction comes to the fore. The gene discussed is LY96; the disease is depressive symptom measurement.