NLRP3 and arthritic joint disease: At this stage, a range of NLRP3 inflammasome-related drugs and intervention strategies for the treatment of arthritis are mainly based on the NLRP3-mediated pyroptosis pathway, and can be divided into the following categories: 1) drugs and tactics that directly block or inhibit the NLRP3-mediated pyroptosis; 2) drugs and tactics that indirectly influence the NLRP3-mediated pyroptosis by modulating its classical activation pathway.