Simultaneously, non-specific chemokines CXCL9, CXCL10, and CXCL11 are produced at the site of inflammation, which may attract Th1 cells and γδT cells from the intestinal site of patients with IBD expressing the receptor CXCR3 to the skin site (21, 105) (Figure 1). This evidence concerns the gene CXCL11 and inflammatory bowel disease.