In addition to the evidence provided by Shen et al (6), who demonstrated that Ube2v1 promoted CRC metastasis, and the evidence from the study by Wu et al (19), which demonstrated that Ube2v1 promoted breast cancer metastasis, Ren et al (8) found that a high expression of Ube2v1 was associated with the poor prognosis of patients with cervical cancer, and Dikshit et al (20) demonstrated that the silencing of Ube2v1 reduced malignant melanoma growth. The gene discussed is UBE2V1; the disease is breast carcinoma.