AQP8 and malignant colon neoplasm: The analysis results showed that the expression levels of AQP8 (P = 0.022), CXCL-8 (P = 0.042), and ZG16 (P = 0.044) were significantly associated with the prognosis of colon cancer, and the high expression of the above three genes was related to their good prognosis, see Figure 6.