This finding is in concordance with a previous study in which extracellular mRNA of CCND2, BCL2, MYC, LMO2, and BCL6 was detected in only 14%, 10%, 10%, 10%, and 5% of DLBCL plasma samples, respectively, but in all of the matched tissue samples (40). Here, MYC is linked to diffuse large B-cell lymphoma.