GSEA between the lymphoma samples and healthy controls showed enrichment of several hallmark gene sets, including interferon type I and II response, interleukin-6/Janus Kinase 2/Signal Transducer and Activator of Transcription 3 (IL-6/JAK/STAT3) signaling, Tumor Necrosis Factor (TNF) alpha signaling via Nuclear factor kappa-light-chain-enhancer of activated B-cells (NF-κB), epithelial mesenchymal transition, inflammatory response, and organization/degradation of the extracellular matrix (ECM). The gene discussed is JAK2; the disease is lymphoma.