The KEGG enrichment functions of MAP1LC3B (Figure 8D) include primary immunodeficiency, ErbB signaling pathway, adipocytokine signaling pathway, cell adhesion molecules cams, intestinal immune network for IgA production, leukocyte trans endothelial migration, B cell receptor signaling pathway, allograft rejection, and insulin signaling pathway. This evidence concerns the gene INS and inborn error of immunity.