Initially, we analyzed the expression levels of m6A regulators in colon cancer, including ALKBH5, METTL3, FTO, METTL14, HNRNPC, WTAP, YTHDF2, RBM15, YTHDF1, ZC3H13, YTHDC2, YTHDC1. The gene discussed is METTL3; the disease is malignant colon neoplasm.