Dong et al. (2020) highlighted lncRNA PCAT6’s role in augmenting breast cancer progression through VEGFR2 modulation. Lang et al. (2021) found that the lncRNA PCAT6 could enhance IGF1R mRNA stability through the PCAT6/IGF2BP2/IGF1R RNA-protein complex, which was induced in an m6A manner. In tongue squamous cancer, Jiang et al. (2022) noticed that the lncRNA SNHG26 could enhance cell malignant biological behaviors and cisplatin resistance of cancer by affecting the PGK1/Akt/mTOR signaling. The gene discussed is IGF2BP2; the disease is cancer.