Initially, we analyzed the expression levels of m6A regulators in colon cancer, including ALKBH5, METTL3, FTO, METTL14, HNRNPC, WTAP, YTHDF2, RBM15, YTHDF1, ZC3H13, YTHDC2, YTHDC1. Here, ALKBH5 is linked to malignant colon neoplasm.