Initially, we analyzed the expression levels of m6A regulators in colon cancer, including ALKBH5, METTL3, FTO, METTL14, HNRNPC, WTAP, YTHDF2, RBM15, YTHDF1, ZC3H13, YTHDC2, YTHDC1. This evidence concerns the gene YTHDC1 and malignant colon neoplasm.