STK11 and hepatocellular carcinoma: In circLARP1B−/− HCC mice upon AAV8‐shLkb1 application, liver tumor number and size, and lung metastases were as worse as what happened in the WT HCC mice (Figure 10a,b), indicating strongly that Lkb1 was the key downstream factor in hepatocytes for the effects of circLARP1B.