USP11 deficiency has been reported to have anti-fibrotic and anti-inflammatory effects in a mice model of hyperuricemia nephropathy and folic acid-induced renal fibrosis (Shi et al. 2023).Zhang et al. found that knockdown of USP11 inhibited the release of pro-inflammatory cytokines following cerebral hemorrhage (Zhang et al. 2021). The gene discussed is USP11; the disease is renal fibrosis.