PRM analysis revealed that recombinant complement factor H-related protein 5 (CFHR5), complement component 9 (C9), and mannose-binding lectin 2 (MBL2) were significantly elevated in NSCLC patients with metastasis compared to nonmetastatic NSCLC patients and healthy individuals (Fig. 5A). Here, MBL2 is linked to non-small cell lung carcinoma.