Transcription co-activator CITED2 has been found to contribute in maintaining proper somatosensory neocortical length, neuronal connectivity, and neocortical development.306 Conditional knockout of CITED2 in the forebrain of mice led to aberrant neocortical development, which can be associated with ADHD.307 Gao et al.308 proved that haploinsufficiency of KDM6B can be linked to ADHD related behaviors in mice. This evidence concerns the gene KDM6B and attention deficit-hyperactivity disorder.