KMT2A and cancer: KMT2A (histone-lysine N-methyltransferase 2A, former MLL) is a transcriptional coactivator with histone H3 lysine 4 (H3K4) methyltransferase activity.414 KMT2A is popularly known to be associated with acute leukemias, especially in infants, where it mostly interacts with six partner genes (AFF1, MLLT3, MLLT10, MLLT1, ELL, AFDN).415 However, a recent study has highlighted that KMT2A is also prevalent in cervical cancer, where it promotes cancer cell growth by regulating VADC1 (Voltage-dependent anion-selective channel 1).