In this study, we found that downregulation of TAB182 increases the proliferation, colony formation, migration, and invasion of TNBC cells, consistent with the study of T. Ohishi and colleagues [24], who found a low expression level of TAB182 in pancreatic cancer cells and found that TAB182 deletion played an essential role in cell motility and invasion. This evidence concerns the gene CNOT12 and pancreatic neoplasm.