We then conducted a KEGG analysis (Fig. 3F), which revealed that the Hippo signaling pathway, basal cell carcinoma, homologous recombination, arrhythmogenic right ventricular cardiomyopathy, and PI3K-Akt signaling pathway were the predicted significantly enriched signaling pathways in TAB182 KD cells, consistent with the results of GO analysis. The gene discussed is CNOT12; the disease is Arrhythmogenic right ventricular dysplasia.