Some reports pointed out the part of ELF1 has tumor-promoting effects in glioma [28, 29], oral squamous cell carcinoma [30], choroidal melanoma [31], endometrial carcinoma [32], acute myeloid leukemia [33], nasopharyngeal carcinoma [34], and osteosarcoma [35], while others have reported a tumor-suppressive function in Hodgkin lymphoma [36] and prostate cancer [37]. The gene discussed is ELF1; the disease is oral cavity squamous cell carcinoma.