Our research findings indicate that a higher volume of PAT is an independent predictive factor for worse prognosis in patients with IPF (HR 2.44 [95% CI 1.10, 5.45], p = 0.029), and it is associated with higher serum IL-6 levels (r = 0.29, p = 0.01). Here, IL6 is linked to idiopathic pulmonary fibrosis.