LAG3 and acute myeloid leukemia: Further inhibitory immune checkpoint receptors/ligands such as LAG-3, VISTA, 2B4, B7-H3, B7-H4, and LILRB4 [55, 72], and activating ones (ICOS, OX40, 41BB, CD70, CD28) [17] may be involved in the immune evasion process of AML after allogeneic transplantation, but their exact role remains still unclear.