Meanwhile, FGF1 also activates cancer-related pathways to regulate cell programming by upregulating the expression of Wnt11. The results indicated that antibiotic intervention induced microbiota dysbiosis, inhibition of cell apoptosis, and alteration of gene expression patterns involved in cell programming, suggesting that the interaction homeostasis was disrupted between microbiota and uterine epithelium in the host. The gene discussed is FGF1; the disease is cancer.