CFS is associated with elevated levels of proinflammatory cytokines (TNF-α, IFN-γ, IL-6, and IL-1) [7] and dysregulation of immune cells (decreased T-regulatory cells, persistence of autoantibody-generating autoreactive B cells, and reduced cytotoxicity of natural killer cells) [8, 9]. The gene discussed is IL6; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.