Of the top ranking processes, cardiac muscle contraction (Rank 1), hypertrophic cardiomyopathy (Rank 2), dilated cardiomyopathy (Rank 3) and adrenergic signaling (Rank 4) are known as critical processes in cardiac remodeling, which supported our previously mentioned hypothesis that PRMT1 regulates cardiac remodeling. This evidence concerns the gene PRMT1 and hypertrophic cardiomyopathy.