Besides, results show that B cell naïve (K-M p < 0.0001, HR = 0.36, Logrank p = 0.011) and T cell CD4 memory resting (K-M p = 0.001, HR = 0.48, Logrank p = 0.007) are protective factors in pan-cancer, while NK cells resting (K-M p < 0.0001, HR = 95.33, Logrank p < 0.0001), Mast cells activated (K-M p < 0.0001, HR = 16.28, Logrank p < 0.0001), and Neutrophils (K-M p < 0.0001, HR > 100, Logrank p < 0.0001) are risky factors in pan-cancer (Figure 3C). This evidence concerns the gene CD4 and cancer.