NOS3 and type 2 diabetes mellitus: Also, cEPCs (CD34+/CD34+ KDR+) and CACs (KDR+ eNOS+ collagen type 1 Col1+) levels were found reduced in T2DM patients, while smooth muscle progenitor cells (SMPCs: CD14+ CD105+) levels did not change, causing an imbalance in the cEPCs/CACs-SMPCs ratios in these patients [102].