On the other hand, although DN has been mostly related to a reduction in the EPCs number [152], similar levels of EPCs (Dil-acLDL+ FITC‐UEA‐I+ CD34+) were found in T1DM patients with and without DN, where DN patients faced a higher CVD risk, due to the longer diabetes duration, poorer glycaemic control and higher very low-density lipoprotein (VLDL) and triglycerides [153]. This evidence concerns the gene CD34 and type 1 diabetes mellitus.