The AUC values of the ROC curves were 0.848 for ABCB1 (Fig. 6G), 0.859 for CD247 (Fig. 6H), 0.843 for DSC1 (Fig. 6I), 0.807 for KIR2DL3 (Fig. 6J), and 0.907 for MX2 (Fig. 6K), indicating that the five key genes have high diagnostic value in evaluating the progression of SLE. This evidence concerns the gene KIR2DL3 and systemic lupus erythematosus.