In Fig. 6A-E, the expression of ABCB1, CD247, DSC1 and KIR2DL3 was significantly downregulated in SLE samples, while the expression of MX2 was significantly upregulated, indicating that they might have critical roles in the development of SLE (all P < 0.01). This evidence concerns the gene MX2 and systemic lupus erythematosus.