The AUC values of the ROC curves were 0.848 for ABCB1 (Fig. 6G), 0.859 for CD247 (Fig. 6H), 0.843 for DSC1 (Fig. 6I), 0.807 for KIR2DL3 (Fig. 6J), and 0.907 for MX2 (Fig. 6K), indicating that the five key genes have high diagnostic value in evaluating the progression of SLE. The gene discussed is DSC1; the disease is systemic lupus erythematosus.