In addition, immune-related pathways such as allograft rejection, mismatch repair, and protein export were significantly enriched in the high ABCB1 subgroup (Fig. 8A), but pathways such as osteoclast differentiation and type II diabetes mellitus were enriched in the low ABCB1 subgroup (Supplementary Fig. 2A). This evidence concerns the gene ABCB1 and type 2 diabetes mellitus.