In addition, RT-qPCR was performed to analyze the relative expression of the five optimal key genes in SLE and healthy control samples, and the results showed that except for DSC1, the expressions of other genes (ABCB1, CD247, KIR2DL3 and MX2) were consistent with the results of biological information analysis. The gene discussed is CD247; the disease is systemic lupus erythematosus.