In Fig. 6A-E, the expression of ABCB1, CD247, DSC1 and KIR2DL3 was significantly downregulated in SLE samples, while the expression of MX2 was significantly upregulated, indicating that they might have critical roles in the development of SLE (all P < 0.01). The gene discussed is DSC1; the disease is systemic lupus erythematosus.