Strikingly, after correlation analysis between hsa-miR-205-5p and its targets in PC, we found that only the expression of BMP and Activin Membrane-Bound Inhibitor (BAMBI) was significantly (negatively) associated with the expression level of hsa-miR-205-5p (Supplementary Figs. 2 and 6e). This evidence concerns the gene BAMBI and pachyonychia congenita.