STAT4 and osteoporosis: In addition, the results of drug sensitivity analysis showed that there was a significant positive correlation between Palbociclib and miR-141 expression, but a significant negative correlation between Palbociclib and STAT4 expression, indicating that Palbociclib may mediate the degradation of STAT4 mRNA by acting on miR-141 to inhibit the development of osteoporosis.