A single nucleotide polymorphism in the 3′UTR of the KRT81 gene is associated with a higher risk of gastric cancer,[15] worse prognosis in non‐Hodgkin's lymphoma,[14] increased recurrence in non‐small‐cell lung cancer,[17] and lower survival in multiple myeloma.[18] KRT81 is also currently being developed as a marker for quasi‐mesenchymal pancreatic ductal adenocarcinoma, the most aggressive subtype of pancreatic cancer,[16] but whether the full‐length or truncated isoform is expressed should be further investigated. Here, KRT81 is linked to pancreatic neoplasm.