Adoptive transfer of bone‐marrow derived GCA+ immune cells into AD animal model clarified that these cells preferentially migrated into the brain via the C‐C Motif Chemokine Receptor 10 (CCR10)‐C‐C Motif Chemokine Receptor 10 (CCL28) axis and accelerated AD development. This evidence concerns the gene CCL28 and Alzheimer disease.