Similar to us, Kanner et al. (41) reported a significant positive correlation between serum S100B levels and tumor size only for VS tumors (n = 6) but not for all other analyzed solid tumors, including glial tumors (n = 8), metastatic tumors (n = 27, predominantly lung and breast carcinoma), meningiomas (n = 8), and chondroma (n = 1). The gene discussed is S100B; the disease is glioma.