MEF2A and coronary artery disorder: In fact, various studies have confirmed the association of MEF2A polymorphisms with the autosomal dominant Coronary Artery Disease (adCAD1) and Myocardial Infarction (MI) [21, 46, 47], and the belief that approximately 2% of CAD is a result of mutations in the MEF2A gene [29], especially, the mutations within exon 11, where various insertion/deletion and substitution polymorphisms like a common variant (CAG)n polymorphism [48, 49].