EPHX1 and Sepsis: Here we find that sepsis, of bacterial or viral origin, is accompanied by an eicosanoid storm with elevated levels of COX (PGE2, PGD2, TxA2), LOX (12‐HETE and LTE4) and EPOX products (11(12)–14(15)‐DHETs) of AA, the ECs AEA and 2‐AG, along with the LA‐derived DiHOMEs.