INS and diabetic cardiomyopathy: Interestingly, functional enrichment analysis of KEGG terms indicated among the overrepresented pathways, Insulin, Thyroid, Diabetic complications, and Diabetic Cardiomyopathy pathways, as well as HIF-1, Ubiquitin proteolysis, and Mitogen-Activated Protein Kinase (MAPK) signaling (Figure 2C).