SIRT1 and cancer: In agreement with these findings, Pramanik et al. (2014) demonstrated that the inhibitory influence exerted by CAP on SIRT1 is not limited to a few human cancers in vitro by adding two cell types of pancreatic adenocarcinoma (BxPC-3 and AsPC-1 cell lines) and a squamous cell carcinoma (L3.6PL cell line) to the list.