In order to confirm that the impact of the effect allele at the variant on the levels of TNFα and IL7 is not due to obese or diabetic or hypertensive subjects in the cohort, we performed allele-based logistic regression analysis to evaluate the risk of disorders (diabetes, obesity, and hypertension) due to the variant (Table 3). Here, IL7 is linked to obesity due to melanocortin 4 receptor deficiency.