JAK3 and glioblastoma: Herein, we used the specific JAK3 inhibitors WHI-P131 (4-(4′-hydroxylphenyl)-amino-6,7-dimethoxyquinazoline) and PF-956980 (((3R,4R)-4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)(pyrrolidin1-yl)methanone) to evaluate their efficacy in preventing GBM cell proliferation, inducing their differentiation, and in downregulating their stemness characteristics.