HNRNPL and Cognitive impairment: An integrative analysis of the metabolome and proteome of the cortex of As-exposed rats yields potential biomarkers related to cognitive impairment caused by this metalloid; these included the overexpression of apolipoprotein E, decrease in mitochondrial complex IV, alteration of SOD1, dysregulation of GSH metabolism, and increased of heterogeneous nuclear ribonucleoprotein L (hnRNP L, an RNA processing factor, and an RNA-binding protein) expression [257].