Though a recent study demonstrated Ang 1-7-mediated anti-inflammatory and anti-apoptotic effects in the aortic aneurysm [23], the precise mechanism of Ang 1-7-mediated antagonism of Ang II is still being investigated as the Ang 1-7/Mas receptor axis has been shown to counteract Ang II/AT1R axis in cardiovascular diseases [24,25]. The gene discussed is AGT; the disease is cardiovascular disorder.