TNF and nervous system disorder: However, some of them have shown that in the model of existing nervous system diseases, such as cerebral ischemia-reperfusion injury, electroconvulsive therapy injury, cobalt chloride (CoCl2)-induced injury, TNF-α-induced injury and sleep deprivation-induced injury, propofol plays a neuroprotective role by regulating autophagy, and improves the degree of nerve damage.