Similarly, diminished expression of miR-1, miR-20a, miR-28, miR-95, miR-146a, miR-335, and miR-625 in PBMCs of pregnant MS patients was discovered to upregulate their targets PD-L1 and PD-L2, potentially contributing to a lower recurrence rate of MS in the pregnant population [46]. The gene discussed is PDCD1LG2; the disease is myeloid sarcoma.