TNF and neoplasm: In addition, important tumor pathways, such as Wnt, MAPK, Notch, JAK-STAT, PD-1/PD-L1, mTOR, TNF, HIF-1, and ErbB, are all related to the risk score, and pathways and functions related to disulfidptosis and ferroptosis are also related to the risk score (Fig. 8C).