S100A12 and prostate cancer: Furthermore, the study on urinary S100/calgranulin concentrations evaluated cases of UC and PCA combined in one group [25], and tissue S100A12+ cell counts were higher in the UC group than in NNUTD cases [42], which might have contributed to higher urinary S100A12 concentrations in dogs with urogenital neoplasia irrespective of the contribution of prostatic cancer cases.