In terms of serum CXCL13 and galectin-9 levels effects on OS, we found that patients with low levels of serum CXCL13 were significantly (p = 0.0443) associated with longer OS, while low galectin-9 serum levels were not significantly associated with longer OS in CLL (Table S5 and Fig. 3E and F). The gene discussed is CXCL13; the disease is B-cell chronic lymphocytic leukemia.