Supporting our earlier findings, we discovered a statistically significant relationship between male gender, spleen size, hemoglobin levels, platelet counts, β2-microglobulin, LDH, CD38%, 17p del, serum CXCL13, serum galectin-9, and high-risk CLL (Table S3). The gene discussed is HLA-G; the disease is B-cell chronic lymphocytic leukemia.