GPT and central nervous system cancer: Furthermore, we found that several ALT-associated cancers, including sarcomas (18%; OR = 6.47; P = 1.95 × 10−5) and low-grade gliomas (12.3%; OR = 3.92; P = 4.1 × 10−3), had the highest rate of GRTR+ loose ends relative to other tumor types (Fig. 3k).