Interestingly if focusing on the proportion of the top two TSSs in T cells (TSS1 and TSS3), we further found that proportion of the minor TSS (TSS1, LIMS1-215) shows a significant up-regulation in cancer condition (NPC) compared to NHL (Fig. 4E), consistent with the trend of expressed cell proportions across patients (Supplementary Fig. S19SA, B). This evidence concerns the gene LIMS1 and non-Hodgkin lymphoma.