This percentage is in the range of incidence referred in different studies, which is of 3% to 30%, and is also similar to the percentage found in the population of pregnant women without SLE (∼ 5%).5, 12, 13, 18, 22, 23There is a well-described relationship between PE and the existence of lupus nephritis,14, 24as well as with some other risk factors, such as positive antiphospholipid antibodies, APS, hypocomplementemia, and positive anti-RNP or anti-dsDNA antibodies.5, 8, 18, 24, 25, 26. This evidence concerns the gene RNPC3 and systemic lupus erythematosus.