BRCA2 and esophageal squamous cell carcinoma: Of the total 464 individuals who had TT genotype of the ALDH2 rs10744777, the frequency of the BRCA2 p.K3326* variant was 5.49% (9 out of 164) among ESCC cases and 1.00% (3 out of 300) among controls (OR = 5.75, 95% CI = 1.53–21.5, P = 0.005).