PROS1 and infection: To further investigate the possible relationship between the viral DNA replication of HvAV-3h and host detoxification enzyme activity, a correlation matrix analysis was performed to assess the changes in the viral DNA copies caused by infection with HvAV-3h blocked by different structural proteins’ antisera (3H-43, 3H-53, 3H-107, and 3H-117) (Fig. 3C) and the subsequent changes in host larval detoxification enzyme activities (Fig. 6A).